Article
The heterogeneity of idiopathic Parkinson's disease.
Journal of neurology - 1 Feb 2002
Foltynie Thomas, Brayne Carol, Barker Roger A
Abstract excerpt
The diagnosis of Idiopathic Parkinson's disease (IPD) requires post mortem neuropathological confirmation to be secure, since there is marked heterogeneity in the clinical phenotype of these patients. Pathologically confirmed IPD encompasses a spectrum of microscopic appearances with respect to the extent and distribution of Lewy Body deposition, which may reflect the clinical phenotypes observed during life. In...
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