Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

First clinical study of germline-targeting strategy: One step closer to a successful bnAb-based HIV vaccine

1 Jan 2023

Abstract excerpt

The epidemic of human immunodeficiency virus type 1 (HIV-1) remains a major threat to global public health, with approximately 38 million people living with HIV-1 worldwide. However, a prophylactic vaccine against HIV-1 is not available yet. In a recent study,1Leggat D.J. Cohen K.W. Willis J.R. et al.Vaccination induces HIV broadly neutralizing antibody precursors in humans.Science. 2022; 378: eadd6502Crossref...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36747593
DOI: 10.1016/j.xinn.2023.100374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

First clinical study of germline-targeting strategy: One step closer to a successful bnAb-based HIV vaccinePMID 36747593Read ↗

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.Semantic proximity Read ↗

Vaccination induces HIV broadly neutralizing antibody precursors in humans.Semantic proximity Read ↗

Germline-Targeting Strategies to Induce bNAbs against HIV-1Semantic proximity Read ↗

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogenSemantic proximity Read ↗

Rational HIV Immunogen Design to Target Specific Germline B Cell ReceptorsSemantic proximity Read ↗

Structural insights into VRC01-class bnAb precursors with diverse light chains elicited in the IAVI G001 human vaccine trialSemantic proximity Read ↗

Vaccine Induction of Heterologous HIV-1 Neutralizing Antibody B Cell Lineages in HumansSemantic proximity Read ↗

Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humansSemantic proximity Read ↗

Structural insights into VRC01-class bnAb precursors with diverse light chains elicited in the IAVI G001 human vaccine trialSemantic proximity Read ↗

Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.Semantic proximity Read ↗

<scp>HIV</scp>‐1 neutralizing antibodies: understanding nature's pathwaysSemantic proximity Read ↗

Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.