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A Proteoform-Resolved Atlas of Human Cardiac Histones

2026-02-10

Abstract excerpt

<title>Abstract</title> <p>Histones variant composition and post-translational modifications (PTMs) of core and linker histones jointly orchestrate chromatin architecture and tissue-specific gene regulation. However, capturing the full complexity of the “histone code” in native human tissues remains challenging. Here we present a human cardiac histone proteoform atlas—comprising intact histone variants with combi...

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Literature Corpus work
c341ac17-1912-50c5-bb17-c7146ccfd09f
DOI
10.21203/rs.3.rs-8811072/v1
Open publication

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A Proteoform-Resolved Atlas of Human Cardiac HistonesDOI 10.21203/rs.3.rs-8811072/v1
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