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Variation in bulk RNA-seq and estimated cell type proportion using deconvolution when comparing pancreatic cancer samples within the same individual

2025-05-06

Abstract excerpt

<h4>Introduction: </h4> There is great promise in using genomic data to inform individual cancer treatment plans. Assessing intratumor genetic heterogeneity, studies have shown it may be possible to target biopsies to tumor subclones driving disease progression or treatment resistance. Here, we explore if the interpretation of tumor gene expression analysis varies across two specimens from the same patient. <h4>Me...

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Literature Corpus work
c2fab297-a4d4-5466-956f-170dc9d387fb
DOI
10.1101/2025.05.05.25326976
Open publication

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Variation in bulk RNA-seq and estimated cell type proportion using deconvolution when comparing pancreatic cancer samples within the same individualDOI 10.1101/2025.05.05.25326976
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