Article

Developmental exposure to domoic acid targets reticulospinal neurons and leads to aberrant myelination in the spinal cord

2022-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Harmful algal blooms (HABs) produce neurotoxins that affect human health. Developmental exposure of zebrafish embryos to the HAB toxin domoic acid (DomA) causes myelin defects, loss of reticulospinal neurons, and behavioral deficits. However, it is unclear whether DomA primarily targets myelin sheaths, leading to the loss of reticulospinal neurons, or reticulospinal neurons, causing myelin defec...

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Literature Corpus work: c2dc241b-2018-584b-8b17-279c5ba82416
DOI: 10.1101/2022.08.08.503200

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