Article

Sex and estrogen receptor β have modest effects on gene expression in the mouse brain posterior cortex

2020-08-07

Abstract excerpt

<h4>Introduction</h4> Sex differences in brain cortical function affect cognition, behavior, and susceptibility to neural diseases, but the molecular basis of sexual dimorphism in cortical function is still largely unknown. Estrogen and estrogen receptors (ERs), specifically ERβ, the most abundant ER in the cortex, may play a role in determining sex differences in gene expression, which could underlie functional...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c2a9d504-b7bb-571f-a8a7-18b56217da5f
DOI: 10.1101/2020.08.07.241927

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sex and estrogen receptor β have modest effects on gene expression in the mouse brain posterior cortexDOI 10.1101/2020.08.07.241927Read

Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and genderSemantic proximity Read

Relative contribution of gonads and sex chromosomes to sex differences in cell-type gene expression in the mouse medial septum and sex-biased disease riskSemantic proximity Read

Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell typesSemantic proximity Read

Large Scale Gene Expression Meta-Analysis Reveals Tissue-Specific, Sex-Biased Gene Expression in HumansSemantic proximity Read

Sex differences in protein expression in the mouse brain and their perturbations in a model of Down syndromeSemantic proximity Read

Differential regulation of mouse hippocampal gene expression sex differences by chromosomal content and gonadal sexSemantic proximity Read

Multi-omic and spatial analysis of mouse kidneys highlights sex-specific differences in gene regulation across the lifespanSemantic proximity Read

Sex-specific single cell-level transcriptomic signatures of Rett syndrome disease progressionSemantic proximity Read

Transcriptome analysis of male–female differences in prefrontal cortical developmentSemantic proximity Read

Multiomics Analyses Reveal Sex Differences in Mouse Renal Proximal SubsegmentsSemantic proximity Read

Sexual Dimorphism in Gene Expression: A Genome-Wide Study of Tissue and Chromosome DependenciesSemantic proximity Read

Signatures of sex: Sex differences in gene expression in the vertebrate brainSemantic proximity Read