Article

Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) is downregulated in Invasive ductal carcinoma: a potential prognostic marker of breast cancer

2021-05-28

Abstract excerpt

LRIG1 (leucine-rich repeat and immunoglobulin-like domain containing), belongs to LRIG family of transmembrane proteins containing leucine rich repeats. LRIGs are considered as tumor suppressor as they negatively regulate receptor tyrosine kinases. The role of LRIG1 as an EGFR regulator makes it an important marker to be studied in various epithelial-derived cancers. LRIG1 expression was low in Erbb2 + cell lines...

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Literature Corpus work: c288c382-c688-53c3-8bcd-6861963892d7
DOI: 10.21203/rs.3.rs-557273/v1

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