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Article

LRIG1 expression in colorectal cancer

1 Jan 2007

Abstract excerpt

In the present study the expression of LRIG1 (leucine rich repeats and immunoglobin-like domains 1) and its relation to EGFR (epidermal growth factor receptor) was examined in tumour samples and adjacent non-neoplastic tissues from 30 patients with colorectal cancer. The LRIG1 gene, at chromosome 3p14, encodes an intergral membrane protein, which counteracts signalling by receptor tyrosine kinases belonging to...

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PMID: 17851870
DOI: 10.1080/02841860701426823

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