Article

Single molecule long-read real-time amplicon-based sequencing of <i>CYP2D6</i> : a proof-of-concept with hybrid haplotypes

2022-08-18

Abstract excerpt

CYP2D6 is a widely expressed human xenobiotic metabolizing enzyme, best known for its role in the hepatic phase I cytochrome P450 enzyme system, where it metabolizes ∼20% of medications. It is also expressed in other organs including the brain, where its potential role in physiology and mental health traits and disorders is under further investigation. Owing to the presence of homologous pseudogenes in the CYP2D...

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Literature Corpus work: c267e048-4311-5550-a2b0-5a5ad58d7aa8
DOI: 10.1101/2022.08.17.503990

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