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Article

Expression of p16 INK4a in peripheral blood T-cells is a biomarker of human aging

2020-10-30

Abstract excerpt

Expression of the p16INK4a tumor suppressor sharply increases with age in most mammalian tissues, and contributes to an age-induced functional decline of certain self-renewing compartments. These observations have suggested that p16INK4a expression could be a biomarker of mammalian aging. To translate this notion to human use, we determined p16INK4a expression in cellular fractions of human whole blood, and found...

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Identifiers and source

Literature Corpus work
c25ae9d6-7687-540f-8727-6f0f53495078
DOI
10.17615/z25c-0c90
Open publication

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Expression of p16 INK4a in peripheral blood T-cells is a biomarker of human agingDOI 10.17615/z25c-0c90
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