Article

Mucin-mimetic glycan arrays integrating machine learning for analyzing receptor pattern recognition by influenza A viruses

2021-04-17

Abstract excerpt

<h4>ABSTRACT</h4> Influenza A viruses (IAVs) exploit host glycans in airway epithelial mucosa to gain entry and initiate infection. Rapid detection of changes in IAV specificity towards host glycan classes can provide early indication of virus transmissibility and infection potential. IAVs use hemagglutinins (HA) to bind sialic acids linked to larger glycan structures and a switch in HA specificity from α2,3-to α...

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Literature Corpus work: c2291bfd-dff2-5de1-b693-ce6c469c1bbc
DOI: 10.1101/2021.04.17.440161

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