Article

Glycan remodeled erythrocytes facilitate antigenic characterization of recent A/H3N2 influenza viruses

2020-12-18

Abstract excerpt

During circulation in humans and natural selection to escape antibody recognition for decades, A/H3N2 influenza viruses emerged with altered receptor specificities. These viruses lost the ability to agglutinate erythrocytes critical for antigenic characterization and give low yields and acquire adaptive mutations when cultured in eggs and cells, contributing to recent vaccine challenges. We examined receptor speci...

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Literature Corpus work: fb946de9-369b-5cc1-b064-80f7a7999577
DOI: 10.1101/2020.12.18.423398

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