Article

Hematopoietic and Lung Platelet Biogenesis as a Prognostic Indicator in Idiopathic Pulmonary Fibrosis (IPF)

2022-04-05

Abstract excerpt

<h4>Rationale and objectives</h4> The role of human lung megakaryocytes in homeostasis and their dynamics in disease states remain unknown. We sought to investigate whether megakaryocyte/platelet gene signatures are altered in IPF. <h4>Methods</h4> We analyzed publicly available transcriptome datasets of lung tissue, bronchoalveolar lavage (BAL) cells, and peripheral whole blood from IPF patients and healthy contr...

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Literature Corpus work: c1ff1ff0-1848-50fa-8f9b-68ea287de321
DOI: 10.1101/2022.04.04.22273424

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