Article
IPF-related new macrophage subpopulations and diagnostic biomarker identification - combine machine learning with single-cell analysis
2024-04-05
Abstract excerpt
<title>Abstract</title> <p>Idiopathic Pulmonary Fibrosis (IPF) is a chronic disease with an unknown etiology and lacks specific treatment. Macrophages, as a major component of the lung immune system, play a crucial regulatory role in IPF, especially during the processes of inflammation and fibrosis. However, our understanding of the cellular heterogeneity, molecular characteristics, and clinical relevance of macr...
Topics
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- Cardiac Fibrosis and Remodeling
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Extracellular vesicles in disease
- Ferroptosis and cancer prognosis
- Immune cells in cancer
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Single-cell and spatial transcriptomics
- Systemic Sclerosis and Related Diseases
Identifiers and source
- Literature Corpus work
- ee33ae33-c6c2-55c9-b7e0-b6246e7514de
- DOI
- 10.21203/rs.3.rs-4186525/v1
