Article

Characterization of a novel estrogen- and progesterone-responsive endometrial cancer cell line: HCI-EC-23

2022-08-25

Abstract excerpt

Most endometrial cancers express the hormone receptor estrogen receptor alpha (ER) and are driven by excess estrogen signaling. However, evaluation of the estrogen response in endometrial cancer cells has been limited by the availability of hormonally responsive in vitro models, with one cell line, Ishikawa, being used in most studies. Here, we describe a novel, adherent endometrioid endometrial cancer (EEC) cell...

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Literature Corpus work: c1d0cae8-eeeb-5036-9038-869cfb9b2fe3
DOI: 10.1101/2022.08.25.505203

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