Article

<i>In vivo</i> generation of post-infarct mouse cardiac muscle by cardiomyocyte progenitors produced with a reproducible laminin-promoted human stem cell differentiation system

2018-11-26

Abstract excerpt

<h4>ABSTRACT</h4> Regeneration of human heart muscle after injury is extremely limited and an unmet clinical need. Despite extensive research, there are no methods for the reproducible generation of clinical quality stem-cell-derived cardiovascular progenitors (CVPs). Here, we identified laminin-221 (LN-221) as the main cardiac laminin, which was produced here as human recombinant protein, and showed that LN-221...

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Literature Corpus work: c1aaac95-3276-5cd9-9a8d-621687e59dbd
DOI: 10.1101/478883

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