Article

<i>In vitro</i> generation of human embryonic stem cell-derived heart organoids possessing physiological ion currents

2022-05-16

Abstract excerpt

Recently, methods for in vitro organogenesis have been broadly developed due to their strong potential for human applications in medicine. In the present study, we optimized the culturing method of human heart organoids (hHOs) from embryonic stem cells (ESCs) in the presence of the highly concentrated laminin-entactin and fibroblast growth factor 4. The resulting hHOs showed distinctive cardiac morphology with at...

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Literature Corpus work: e66124df-f447-5ea1-9e1b-f70c031d67da
DOI: 10.1101/2022.05.15.491904

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