Article

Systemic Delivery of Human Mesangioblasts mediated by a Nanofiber Scaffold restores Dystrophin Expression in Immunodeficient Dystrophic Mice

2026-04-02

Abstract excerpt

Delivery of cells or vectors in advanced therapies is probably the major challenge for genetic disorders that affect a large part of the body such as Duchenne Muscular Dystrophy (DMD). Here, we describe a novel approach for systemic cell delivery based upon an implantable bio-scaffold composed of aligned polycaprolactone nanofibers coated with laminin, able to support adhesion and extensive proliferation of mesode...

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Literature Corpus work: 3bd756bf-56b4-5619-9e09-1f9934b2a734
DOI: 10.64898/2026.03.31.715524

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