Article

EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes

2024-10-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) are an emerging model for determining drug effects and modeling disease. Specialized devices can generate Extracellular Field Potential (EFP) measurements from these cells, analogous to the ventricular complex of the electrocardiogram. <h4>Objective</h4> The objective of this study was to develop an easy-to-use,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c1a48fe5-e120-5f83-8741-f904d449040a
DOI: 10.1101/2024.10.21.619481

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytesDOI 10.1101/2024.10.21.619481Read

Arrhythpy: An Automated Tool to Quantify and Classify Arrhythmias in Ca <sup>2+</sup> Transients of iPSC-CardiomyocytesSemantic proximity Read

Drug Screening Platform Using Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes and Optical MappingSemantic proximity Read

All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug EvaluationSemantic proximity Read

Field potential Imaging in human iPSC- derived Cardiomyocytes using UHD-CMOS-MEASemantic proximity Read

High-Throughput Phenotyping of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Neurons Using Electric Field Stimulation and High-Speed Fluorescence Imaging.Semantic proximity Read

A Correlation Analysis of Field Potential and Action Potential Biomarkers in Heterogeneous hiPSC-Derived Cardiac TissuesSemantic proximity Read

Cardiac microtissues from human pluripotent stem cells recapitulate the phenotype of long-QT syndrome.Semantic proximity Read

Automated Feature Extraction from Large Cardiac Electrophysiological Data SetsSemantic proximity Read

Creating cell-specific computational models of stem cell-derived cardiomyocytes using optical experimentsSemantic proximity Read

Single-cell ionic current phenotyping elucidates non-canonical features and predictive potential of cardiomyocytes during automated drug experiments.Semantic proximity Read

Development of human iPSC-derived cardiomyocytes-based heart-on-a-chip with customized multi-electrode array for drug-induced cardiotoxicity evaluationsSemantic proximity Read

Noninvasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM.Semantic proximity Read