Article
Gene regulatory network analysis identifies sex-linked differences in colon cancer drug metabolism processes
2018-03-07
Abstract excerpt
Significant sex differences are observed in colon cancer, and understanding these differences is essential to advance disease prevention, diagnosis, and treatment. Males have a higher risk of developing colon cancer and a lower survival rate than women. However, the molecular features that drive these sex differences are poorly understood. We used both transcript-based and gene regulatory network methods to analyz...
Topics
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- Cancer-related molecular mechanisms research
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Treatments and Studies
- Drug Transport and Resistance Mechanisms
- Ferroptosis and cancer prognosis
- Genetic factors in colorectal cancer
- Hormonal Regulation and Hypertension
- Pharmacogenetics and Drug Metabolism
Identifiers and source
- Literature Corpus work
- c1817b36-fadf-533d-908a-c194b3f2578d
- DOI
- 10.1101/277186
