Article

Sex Differences in Cancer Functional Genomics: Gene Dependency and Drug Sensitivity

2025-02-08

Abstract excerpt

Patient sex influences a wide range of cancer phenotypes, including prevalence, response to therapy and survival endpoints. Molecular sex differences across the central dogma have been identified that may drive these phenotypic differences. Despite a growing catalog of specific genomic, transcriptomic and proteomic sex differences in a range of cancer types, their functional consequences remain unclear. To assess...

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Literature Corpus work: 6f5ac62f-2865-5933-a72c-5a9a2bb79342
DOI: 10.1101/2025.02.05.636540

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