Article

Integrative Multi-Omics Framework for Causal Gene Discovery in Long COVID

2025-02-12

Abstract excerpt

<h4>Background</h4> Long COVID, or Post-Acute Sequelae of COVID-19 (PASC), involves persistent, multisystemic symptoms in about 10–20% of COVID-19 patients. Although age, sex, ethnicity, and comorbidities are recognized as risk factors, identifying genetic contributors is essential for developing targeted therapies. <h4>Methods</h4> We developed a multi-omics framework using Transcriptome-Wide Mendelian Randomizat...

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Literature Corpus work: c16f6b67-efd2-5781-92ff-b5f0893ffaf3
DOI: 10.1101/2025.02.09.25321751

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