Article

GLUCOCORTICOIDS REGULATE MITOCHONDRIAL FATTY ACID OXIDATION IN FETAL CARDIOMYOCYTES

2021-04-30

Abstract excerpt

<h4>ABSTRACT</h4> The late gestational rise in glucocorticoids contributes to the structural and functional maturation of the perinatal heart. Here, we hypothesised that glucocorticoid action contributes to the metabolic switch in perinatal cardiomyocytes from carbohydrate to fatty acid oxidation. In primary mouse fetal cardiomyocytes, dexamethasone treatment induced expression of genes involved in fatty acid oxi...

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Literature Corpus work: c13d565d-ce97-5495-afbc-cbd875ece2b7
DOI: 10.1101/2021.04.30.442128

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