Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucocorticoid Receptor‐Binding and Transcriptome Signature in Cardiomyocytes

14 Mar 2019

Abstract excerpt

Background An increase in serum cortisol has been identified as a risk factor for cardiac failure, which highlights the impact of glucocorticoid signaling in cardiomyocytes and its influence in the progression of failure. Dexamethasone, a synthetic glucocorticoid, is sufficient for induction of cardiomyocyte hypertrophy, but little is known of the glucocorticoid receptor (GR) genome-binding and -dependent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Fibrosis and Remodeling
Share to RNA Research and Splicing
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30866692
DOI: 10.1161/jaha.118.011484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucocorticoid Receptor‐Binding and Transcriptome Signature in CardiomyocytesPMID 30866692Read ↗

Glucocorticoid receptor epigenetic activity in the heartSemantic proximity Read ↗

Comprehensive overview of the structure and regulation of the glucocorticoid receptor.Semantic proximity Read ↗

A cross-tissue transcriptomic approach decodes glucocorticoid receptor-dependent links to human metabolic phenotypesSemantic proximity Read ↗

Multifaceted Control of GR Signaling and Its Impact on Hepatic Transcriptional Networks and MetabolismSemantic proximity Read ↗

The Glucocorticoid Receptor in Cardiovascular Health and DiseaseSemantic proximity Read ↗

A guide to changing paradigms of glucocorticoid receptor function—a model system for genome regulation and physiologySemantic proximity Read ↗

Dynamic regulation of glucocorticoid signalling in health and diseaseSemantic proximity Read ↗

Distinct regulation of hippocampal neuroplasticity and ciliary genes by corticosteroid receptorsSemantic proximity Read ↗

Glucocorticoid and adrenergic receptor distribution across human organs and tissues: a map for stress transductionSemantic proximity Read ↗

The human glucocorticoid receptor: molecular basis of biologic function.Semantic proximity Read ↗

Differential Regulation and Function of 5′-Untranslated GR-Exon 1 TranscriptsSemantic proximity Read ↗

Integrative analysis of macrophage ribo-Seq and RNA-Seq data define glucocorticoid receptor regulated inflammatory response genes into distinct regulatory classesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.