Mid‐ to late term hypoxia in the mouse alters placental morphology, glucocorticoid regulatory pathways and nutrient transporters in a sex‐specific manner

Abstract excerpt

Key points Maternal hypoxia is a common perturbation that may impair fetal development and programme sex specific disease outcomes in offspring. There is growing interest in the role of the placenta in mediating the effects of maternal hypoxia on fetal development, particularly in late gestation during maximal fetal growth. Multiple mechanisms have been proposed to play a role in hypoxia induced impairment of...

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