Article

Loss of <i>Slc35a2</i> alters development of the mouse cerebral cortex

2023-11-30

Abstract excerpt

Brain somatic variants in SLC35A2 are associated with clinically drug-resistant epilepsy and developmental brain malformations, including mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE). SLC35A2 encodes a uridine diphosphate galactose translocator that is essential for protein glycosylation; however, the neurodevelopmental mechanisms by which SLC35A2 disruption le...

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Literature Corpus work: c13c5120-3b8d-5b62-a7a6-2602829ae55b
DOI: 10.1101/2023.11.29.569243

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