Article

Mutation profile and molecular heterogeneity in mismatch repair deficient endometrial carcinoma

2024-06-26

Abstract excerpt

<title>Abstract</title> <p>Endometrial carcinoma (EC) with deficient DNA mismatch repair (dMMR) is a specific molecular entity with unique clinicopathological features. Herein, we depicted the mutation profile of dMMR ECs and explored the molecular heterogeneity among dMMR subgroups with different etiologies. Next-generation sequencing based on a 1021-gene panel was applied to 74 dMMR ECs and 43 proficient MMR (p...

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Literature Corpus work: c11c25e9-e10e-5836-9b4f-209ebca89aa5
DOI: 10.21203/rs.3.rs-4537456/v1

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