Article

Dihydrotanshinone I Induces Autophagic Cell Death in Ovarian Cancer by Disrupting the SORT1-Mediated Autophagy–Lysosome Pathway

2025-06-23

Abstract excerpt

Ovarian cancer (OC), a common malignancy of the female reproductive system, has the highest mortality rate among gynecological cancers. A distinguishing feature of OC cells (OCCs) is their reduced autophagic flux compared with normal cells. This phenomenon indicates that excessive autophagy activation or impaired autophagosome–lysosome fusion may lead to OCC death. This study investigated the anti-OC effects of di...

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Literature Corpus work: c0fc8a49-e7b6-5ca6-80bd-bba666d9bddc
DOI: 10.1016/j.eng.2025.06.020

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Dihydrotanshinone I Induces Autophagic Cell Death in Ovarian Cancer by Disrupting the SORT1-Mediated Autophagy–Lysosome PathwayDOI 10.1016/j.eng.2025.06.020Read

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