Article

Re-expression of SynGAP Protein in Adulthood Improves Translatable Measures of Brain Function and Behavior in a Model of Neurodevelopmental Disorders

2018-11-20

Abstract excerpt

<h4>Background</h4> Neurodevelopmental disorder (NDD) risk genes have pleiotropic biological functions, such as control over both developmental and non-developmental processes that influence disease-related phenotypes. Currently, it remains unclear how developmental versus non-developmental processes influence the duration and/or effectiveness of permissive treatment windows for NDDs. SYNGAP1 haploinsufficiency...

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Literature Corpus work: 076cf596-fab4-5e4f-a79a-4f3aab745f63
DOI: 10.1101/474965

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