Article

Effective NGN2-based neuronal programming of hiPSCs in an automated microfluidic platform

2022-10-17

Abstract excerpt

Neurodegenerative diseases represent an increasing health burden, with a worrying lack of models recapitulating the hallmarks of the pathology. Recently, lab-on-a-chip technology has opened new reliable alternatives to conventional in vitro models able to replicate key aspects of human physiology. For instance, microfluidics allows to mimic the extracellular accumulation of misfolded proteins in the finely contro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c09135ce-b26c-5afb-aa0b-64c54e6a16c0
DOI: 10.1101/2022.10.13.512042

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Effective NGN2-based neuronal programming of hiPSCs in an automated microfluidic platformDOI 10.1101/2022.10.13.512042Read

Neuromuscular junction‐on‐a‐chip: ALS disease modeling and read‐out development in microfluidic devicesSemantic proximity Read

Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem CellsSemantic proximity Read

The Shift from 2D to 3D Cell Culture in Neurobiology: Implications for Precision Medicine and Organ-on-Chip TechnologiesSemantic proximity Read

A multimodal 3D neuro-microphysiological system with neurite-trapping microelectrodesSemantic proximity Read

Vascular-Perfusable Human 3D Brain-on-ChipSemantic proximity Read

Development of a multi-sensor integrated midbrain organoid-on-a-chip platform for studying Parkinson’s diseaseSemantic proximity Read

Culture of Human iPSC-Derived Motoneurons in Compartmentalized Microfluidic Devices and Quantitative Assays for Studying Axonal Phenotypes.Semantic proximity Read

Rapid, Growth Factor-Reduced Differentiation of Functional Neurons from hiPSCsSemantic proximity Read

Cultivation and characterization of human midbrain organoids in sensor integrated microfluidic chipsSemantic proximity Read

Advances and challenges in modeling inherited peripheral neuropathies using iPSCsSemantic proximity Read

Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans modelsSemantic proximity Read

Microfluidic based human-on-a-chip: A revolutionary technology in scientific researchSemantic proximity Read