Back to search

Article

Microfluidic based human-on-a-chip: A revolutionary technology in scientific research

2021-04-01

Abstract excerpt

Detrimental drug toxicity and failure in efficacy during clinical trials is one of the major hurdles faced by the pharmaceutical companies. Conventionally, preclinical safety evaluation is performed in 2D cell cultures and animal models. However, the response of a drug seen in laboratory animals and cells grown as monolayers differs from how cells inside a human body respond. This is due to the lack of multi-organ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c96e3895-e8aa-5e5a-bc22-4766f1fa3905
DOI
10.1016/j.tifs.2021.02.049
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Microfluidic based human-on-a-chip: A revolutionary technology in scientific researchDOI 10.1016/j.tifs.2021.02.049
User-View on Organ-on-a-Chip TechnologySemantic proximity
Organs-on-a-Chip Database (OOCDB): A Comprehensive, Systematic and Real-time Organs-on-a-chip DatabaseSemantic proximity
An Array of Gut-on-a-Chips for Drug DevelopmentSemantic proximity
Training the next generation of researchers in the Organ-on-Chip fieldSemantic proximity
Towards an autologous iPSC-derived patient-on-a-chipSemantic proximity
A Generic Pump-free Organ-on-a-Chip Platform for Assessment of Drug BioavailabilitySemantic proximity
The Tumor-on-Chip: Recent Advances in the Development of Microfluidic Systems to Recapitulate the Physiology of Solid TumorsSemantic proximity
Developmentally inspired human ‘organs on chips’Semantic proximity
Development and evaluation of a microfluidic human testicular tissue chip: a novel in vitro platform for reproductive biology and pharmacology studiesSemantic proximity
Biomimetic microsystems for cardiovascular studies.Semantic proximity
A High-Throughput Microphysiological Liver Chip System to Model Direct and Idiosyncratic Drug-Induced Liver Injury Using Human Liver OrganoidsSemantic proximity
Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies.Semantic proximity
Select a neighboring publication to make it the new centre.