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Article

Effects of ready to drink teas on AhR- and PXR-mediated expression of cytochromes P450 CYP1A1 and CYP3A4 in human cancer cell lines and primary human hepatocytes

2012-04-01

Abstract excerpt

A variety of xenobiotics are taken in the diet and they can interfere with regulatory pathways of drug metabolizing enzymes in humans. This can result in food–drug interactions, which is undesirable clinical situation where drug pharmacokinetics are influenced by dietary compounds. Xenobiotics-mediated food–drug interactions include the induction of drug metabolizing cytochromes P450. The expression of the most im...

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Literature Corpus work
c061be2a-3bd7-5f89-97c5-58a363c18f85
DOI
10.1016/j.foodchem.2011.09.104
Open publication

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Effects of ready to drink teas on AhR- and PXR-mediated expression of cytochromes P450 CYP1A1 and CYP3A4 in human cancer cell lines and primary human hepatocytesDOI 10.1016/j.foodchem.2011.09.104
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