Article
Effects of ready to drink teas on AhR- and PXR-mediated expression of cytochromes P450 CYP1A1 and CYP3A4 in human cancer cell lines and primary human hepatocytes
2012-04-01
Abstract excerpt
A variety of xenobiotics are taken in the diet and they can interfere with regulatory pathways of drug metabolizing enzymes in humans. This can result in food–drug interactions, which is undesirable clinical situation where drug pharmacokinetics are influenced by dietary compounds. Xenobiotics-mediated food–drug interactions include the induction of drug metabolizing cytochromes P450. The expression of the most im...
Topics
Open a Topic to create a Post that cites this publication.
- Drug Transport and Resistance Mechanisms
- Eicosanoids and Hypertension Pharmacology
- Estrogen and related hormone effects
- Genomics, phytochemicals, and oxidative stress
- Hormonal Regulation and Hypertension
- Pharmacogenetics and Drug Metabolism
- Phytochemicals and Antioxidant Activities
- Plant Gene Expression Analysis
Identifiers and source
- Literature Corpus work
- c061be2a-3bd7-5f89-97c5-58a363c18f85
- DOI
- 10.1016/j.foodchem.2011.09.104
