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Ethanol Enhances CYP2B6 and CYP2B7 mRNA Expression in Hepatic and Intestinal Cell Models: Evidence for CAR-Dependent Regulation

2026-01-28

Abstract excerpt

<h4>Background: </h4> /Objectives: Using a human liver donor bank, we previously demonstrated a strong correlation between donor history of ethanol consumption and increased hepatic CYP2B6 mRNA, protein, and enzymatic activity, suggesting that ethanol may enhance CYP2B6 expression in vivo. The objective of this study was to determine whether ethanol exposure increases CYP2B6 gene expression in hepatic and intestin...

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Literature Corpus work
5ccd9243-9c60-591c-b0dd-ab32a96748bd
DOI
10.20944/preprints202601.2147.v1
Open publication

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Ethanol Enhances CYP2B6 and CYP2B7 mRNA Expression in Hepatic and Intestinal Cell Models: Evidence for CAR-Dependent RegulationDOI 10.20944/preprints202601.2147.v1
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