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Altered CYP Expression and Function in Response to Dietary Factors: Potential Roles in Disease Pathogenesis

17 Nov 2005

Abstract excerpt

Increasing evidence implicates dietary factors in the progression of diseases, including certain cancers, diabetes and obesity. Diet also regulates the expression and function of CYP genes, which impacts on drug elimination and may also significantly affect disease pathogenesis. Upregulation of CYPs 2E1 and 4A occurs after feeding of experimental diets that are high in fats or carbohydrates; these diets also...

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PMID: 16454693
DOI: 10.2174/138920006774832569

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