Article

Activating P2Y <sub>1</sub> receptors improves function in arteries with repressed autophagy

2021-05-28

Abstract excerpt

<h4>Objective</h4> The importance of endothelial cell (EC) autophagy to vascular homeostasis is evolving. Earlier we reported that purinergic 2Y 1 receptor (P2Y 1 -R) activation rejuvenates shearstress induced nitric oxide (NO) generation in bovine aortic endothelial cells that is otherwise compromised after pharmacological and genetic autophagy repression. Here we determined the translational and functional re...

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Literature Corpus work: c05d0f63-6c97-53e5-a0f2-4bb098ef611d
DOI: 10.1101/2021.05.27.445652

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