Article
Impaired vascular function and repair in patients with premature coronary artery disease.
European journal of preventive cardiology - 1 Dec 2015
Brittan Mairi, Hunter Amanda, Boulberdaa Mounia, Fujisawa Takeshi, Skinner Elizabeth M, Shah Anoop Sv, Baker Andrew H, Mills Nicholas L
Abstract excerpt
BACKGROUND: Endothelial dysfunction is central to the pathogenesis of coronary artery disease, but the role of local and circulating endothelial progenitor cells in maintaining vascular health is poorly understood. We hypothesised that impaired local and circulating vascular repair mechanisms predispose to endothelial dysfunction and the premature onset of coronary artery disease. METHODS AND RESULTS: Patients...
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