Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor irradiation induced immunogenic response: the impact of DNA damage induction and misrepair

21 Aug 2025

Abstract excerpt

Focal tumor irradiation, a cornerstone of cancer therapy, has been increasingly recognized for its capacity to provoke systemic immunogenic responses that extend beyond localized tumor control. Recent advances highlight DNA damage, especially DNA double-strand breaks (DSBs), as a central mediator linking radiotherapy to anti-tumor immune activation. Importantly, DNA misrepair, prevalent in cancer cells with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immune Cell Function and Interaction
Share to Immunotherapy and Immune Responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40841665
DOI: 10.1186/s13014-025-02711-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor irradiation induced immunogenic response: the impact of DNA damage induction and misrepairPMID 40841665Read ↗

Interplay between the DNA Damage Response and Immunotherapy Response in CancerSemantic proximity Read ↗

The DNA damage response in immunotherapy and radiationSemantic proximity Read ↗

Error‐prone DNA repair pathways as determinants of immunotherapy activity: an emerging scenario for cancer treatmentSemantic proximity Read ↗

The complementarity of DDR, nucleic acids and anti-tumour immunity.Semantic proximity Read ↗

The convergence of radiation and immunogenic cell death signaling pathwaysSemantic proximity Read ↗

Exploiting DNA repair pathways for tumor sensitization, mitigation of resistance, and normal tissue protection in radiotherapySemantic proximity Read ↗

Immunomodulatory Effects of RadiotherapySemantic proximity Read ↗

Molecular determinants of immunogenic cell death elicited by radiation therapySemantic proximity Read ↗

The immunological consequences of radiation‐induced DNA damageSemantic proximity Read ↗

Radiation‐Induced Immunogenic Cell Death for Cancer RadioimmunotherapySemantic proximity Read ↗

DNA Damage and Repair Biomarkers of Immunotherapy ResponseSemantic proximity Read ↗

DNA Repair and Signaling in Immune-Related Cancer TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.