Back to search

Article

Clonal Transmission of Emerging Novel <i>Plasmodium falciparum</i> Kelch13 Mutations and Increasing Complexity of Infection in Libreville, Gabon, 2021-2023

2025-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Artemisinin partial resistance (ART-R) in Plasmodium falciparum , due to mutations in the Kelch13 (K13) propeller domain, is spreading across Africa. However, data from Central Africa remain sparse. This study performed molecular surveillance in a peri-urban sentinel site in Libreville, Gabon, from 2021 to 2023 to assess emerging resistance markers and parasite population dynamics. Febrile patie...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
34d8964a-3f96-5459-9205-8eda48e6f6bc
DOI
10.1101/2025.08.07.25333205
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Clonal Transmission of Emerging Novel <i>Plasmodium falciparum</i> Kelch13 Mutations and Increasing Complexity of Infection in Libreville, Gabon, 2021-2023DOI 10.1101/2025.08.07.25333205
Understanding the Global Spread of Artemisinin Resistance: Insights from over 100K <i>Plasmodium falciparum</i> SamplesSemantic proximity
Longitudinal surveillance of kelch13 identifies C469Y, P553L, R561H and A675V mutations associated with artemisinin resistance in Western KenyaSemantic proximity
Emerging threat of Partial Artemisinin Resistance Markers in P. falciparum Parasite Populations in multiple geographical locations in high Transmission Regions of UgandaSemantic proximity
Mapping the prevalence of molecular markers of <i>Plasmodium falciparum</i> artemisinin partial resistance in Africa: a spatial-temporal modelling studySemantic proximity
Clonal spread of<i>Plasmodium falciparum</i>candidate artemisinin partial resistance<i>Kelch13</i>622I mutation and co-occurrence with<i>pfhrp2/3</i>deletions in EthiopiaSemantic proximity
Sentinel surveillance of the WHO-validated Pfkelch13 C580Y artemisinin resistance marker in Plasmodium falciparum isolates from Bangui, Central African RepublicSemantic proximity
Genomic Surveillance Reveals Clusters of <i>Plasmodium falciparum</i> Antimalarial Resistance Markers in Eswatini, a Low-Transmission SettingSemantic proximity
Artemisinin resistant <i>kelch13</i> R622I and RDT negativity approaching predominance in northern Ethiopia and emerging C580Y of African origin threaten falciparum malaria controlSemantic proximity
<i>Plasmodium falciparum</i> genomic surveillance reveals a diversity of <i>kelch13</i> mutations in ZambiaSemantic proximity
Emergence and Spread of Plasmodium falciparum Kelch 13 Mutations in Selected Counties of Kenya: Implications for Responding to Artemisinin Partial Resistance.Semantic proximity
Spatial Surveillance of Plasmodium falciparum Kelch 13 Mutations Reveals Emerging Artemisinin Resistance in KenyaSemantic proximity
A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa.Semantic proximity
Select a neighboring publication to make it the new centre.