Article

Cell cycle dynamics of human pluripotent stem cells primed for differentiation

2019-02-12

Abstract excerpt

Understanding the molecular properties of the cell cycle of human pluripotent stem cells (hPSCs) is critical for effectively promoting differentiation. Here, we use the Fluorescence Ubiquitin Cell Cycle Indicator (FUCCI) system adapted into hPSCs and perform RNA-sequencing on cell cycle sorted hPSCs primed and unprimed for differentiation. Gene expression patterns of signaling factors and developmental regulators...

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Literature Corpus work: bf61a821-bbc3-5302-926c-af0eae423abf
DOI: 10.1101/546291

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