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Exploring the Influence of c-Jun N terminal Kinase Scaffold Proteins on the Spatiotemporal Regulation of JNK Activation in Pancreatic Ductal Adenocarcinoma

2024-12-24

Abstract excerpt

<title>Abstract</title> <p> c-Jun N terminal kinase (JNK) activation plays a significant role in dictating cell fate outcome Especially, in response to cellular stress inducers such as: Sodium Arsenide and Hydrogen peroxide(H2O2). Biochemically, the p38 and JNK-MAPK can activate the SAPK (Stress Activated Protein Kinase) pathways. This same stress granules can also reduce the SAPK apoptotic response. Where the R...

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Literature Corpus work
bf27909f-6f62-528b-a628-1b72bde2bce8
DOI
10.21203/rs.3.rs-4792346/v2
Open publication

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Exploring the Influence of c-Jun N terminal Kinase Scaffold Proteins on the Spatiotemporal Regulation of JNK Activation in Pancreatic Ductal AdenocarcinomaDOI 10.21203/rs.3.rs-4792346/v2
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