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Article

Molecular mechanisms of pancreatic carcinogenesis

24 Nov 2005

Abstract excerpt

Pancreatic ductal adenocarcinoma is one of the most fatal malignancies. Intensive investigation of molecular pathogenesis might lead to identifying useful molecules for diagnosis and treatment of the disease. Pancreatic ductal adenocarcinoma harbors complicated aberrations of alleles including losses of 1p, 6q, 9p, 12q, 17p, 18q, and 21q, and gains of 8q and 20q. Pancreatic cancer is usually initiated by mutation...

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PMID: 16367914
DOI: 10.1111/j.1349-7006.2005.00134.x

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