Article

Major Histocompatibility Complex (MHC) I-induced Endoplasmic Reticulum (ER) Stress mediates the secretion of pro-inflammatory muscle-derived cytokines

2022-07-01

Abstract excerpt

<h4>ABSTRACT</h4> Major histocompatibility complex (MHC) I is an important component of intracellular antigen presentation. However, improper expression of MHC I upon the cell surface has been associated with several autoimmune diseases. Myositis is a rare acquired autoimmune diseases which targets skeletal muscle, and MHC I overexpression on the surface of muscle fibres and immune cell infiltration are clinical...

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Literature Corpus work: bf2131b8-ab03-551a-af71-f03ffe2dc549
DOI: 10.1101/2022.06.29.496997

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