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Article

Myeloid related protein induces muscle derived inflammatory mediators in juvenile dermatomyositis

23 Sept 2013

Abstract excerpt

INTRODUCTION: The aetiopathogenesis of juvenile dermatomyositis (JDM) remains poorly understood. In particular the contribution of monocytes or macrophages, which are frequently observed to be an infiltrate within muscle tissue very early in the disease process, is unknown. We hypothesised that these cells secrete the pro-inflammatory myeloid related protein (MRP) 8/14 which may then contribute to muscle...

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PMID: 24286299
DOI: 10.1186/ar4311

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