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Latent <i>Toxoplasma gondii</i> infection increases soluble mutant huntingtin and promotes neurodegeneration in the YAC128 mouse model of Huntington’s disease

2019-02-15

Abstract excerpt

Toxoplasma gondii causes a prevalent neuroinvasive protozoal pathogen that in immune competent individuals results in latent infection characterized by intra-cellular parasite cysts in brain. Despite life-long infection, the role of latent toxoplasmosis on chronic neurodegenerative processes is poorly understood. Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a dominant CAG repeat...

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Literature Corpus work
bf0fbed0-ee1b-5928-aca9-4dd421301ab8
DOI
10.1101/550624
Open publication

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Latent <i>Toxoplasma gondii</i> infection increases soluble mutant huntingtin and promotes neurodegeneration in the YAC128 mouse model of Huntington’s diseaseDOI 10.1101/550624
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