Effects of latent infection of Toxoplasma gondii strains with different genotypes on mouse behavior and brain transcripts

Abstract excerpt

<title>Abstract</title> <p>Background <italic>Toxoplasma gondii</italic> (<italic>T. gondii</italic>) can cause severe damage to immunodeficient hosts, and also compromise brain structure and function in immunocompetent hosts during latent infection. In China, the two different isolates, <italic>Chinese I</italic> (<italic>ToxoDB#9</italic>) and <italic>Chinese III</italic> are dominant epidemic strains widely s...

Topics

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• Amyloid Precursor Protein Secretases
• Apoptosis Regulatory Proteins
• Aspartic Acid Endopeptidases
• Cognition
• Disease Models, Animal
• Mice
• Mice, Inbred C57BL
• Toxoplasma gondii Research Studies

Identifiers and source

Literature Corpus work

4463259e-a953-5356-8c4b-828b51535820

DOI

10.21203/rs.3.rs-6075517/v1