Article

Hippo Pathway Dysregulation in Thymic Epithelial Tumors (TETs): Associations with Clinicopathological Features and Patients’ Prognosis

2025-05-26

Abstract excerpt

Thymic epithelial tumors (TETs) display a heterogeneous histology and often unpredictable clinical behavior. The Hippo signaling pathway has been implicated in tumorigenesis, but its role in TETs remains poorly characterized. We analyzed the immunohistochemical expression of core Hippo pathway components—YAP1, active YAP (AYAP), TAZ, LATS1, MOB1A, MST1, SAV1, and TEAD4—in 77 TETs. Associations with clinicopatholog...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 609c2aaf-2f12-5be9-be5c-9d686170742f
DOI: 10.20944/preprints202505.2009.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hippo Pathway Dysregulation in Thymic Epithelial Tumors (TETs): Associations with Clinicopathological Features and Patients’ PrognosisDOI 10.20944/preprints202505.2009.v1Read

Unraveling molecular networks in thymic epithelial tumors: deciphering the unique signaturesSemantic proximity Read

The Molecular Landscape of Thymic Epithelial Tumors: A Comprehensive ReviewSemantic proximity Read

Epigenetics of Thymic Epithelial TumorsSemantic proximity Read

Single-Cell Sequencing Illuminates Thymic Development: An Updated Framework for Understanding Thymic Epithelial TumorsSemantic proximity Read

Molecular landscape of thymic epithelial tumors.Semantic proximity Read

Integrated Molecular and Clinical Analysis of Thymic Epithelial Tumors.Semantic proximity Read

The Integrated Genomic Landscape of Thymic Epithelial Tumors.Semantic proximity Read

Genomic landscape and molecularly informed therapy in thymic carcinoma and other advanced thymic epithelial tumors.Semantic proximity Read

Comprehensive Genomic Profiling of 274 Thymic Epithelial Tumors Unveils Oncogenic Pathways and Predictive Biomarkers.Semantic proximity Read

Genomic characterization of thymic epithelial tumors in a real-world datasetSemantic proximity Read

Genetic insights into thymic carcinomas and thymic neuroendocrine neoplasms denote prognosis signatures and pathways.Semantic proximity Read

SNAI1 promotes epithelial-mesenchymal transition and maintains cancer stem cell-like properties in thymic epithelial tumors through the PIK3R2/p-EphA2 AxisSemantic proximity Read