Article

Accurate Identification of Primary Site in Tumors of Unknown Origin (TUO) Using DNA Methylation

2024-12-05

Abstract excerpt

<title>Abstract</title> <p>Tumors of unknown origin (TUO) generally result in poor patient survival and are clinically difficult to address. Identification of the site of origin in TUO patients is paramount to their improved treatment and survival but is difficult to obtain with current methods. Here, we develop a random forest machine learning TUO methylation classifier using a large number of primary and metast...

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Literature Corpus work: 752bc735-4ecb-5df9-84cc-de4a87753bea
DOI: 10.21203/rs.3.rs-3979271/v2

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