Dissecting the coordinated progression of cell states in spatial transcriptomics with CoPro

Abstract excerpt

Spatial transcriptomics enables the study of how cells coordinate their molecular states within tissue, providing insight into both normal function and disease processes. A key challenge is to identify gene expression programs that vary continuously across space and are coordinated between cell types. We present CoPro , a computational framework for detecting the spatially coordinated progression of cellular stat...

Topics

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• Bees
• Gene Expression Regulation
• Gene Regulatory Networks
• Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Neoplasms
• Renal and related cancers
• Renal and Vascular Pathologies
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

b99f2964-ca26-5cc6-b765-6043b76139c7

DOI

10.64898/2026.04.17.719309