Article

Compartmentalization of intestinal bacteria by hepatic ILC3s prevents infections after surgery

2019-09-19

Abstract excerpt

<h4>ABSTRACT</h4> Infections after surgical interventions are assumed to be caused by contamination. We show by analyzing multicentric data of 6561 patients that surgical infections as well as sepsis had a predominantly enteric microbial signature irrespective of the type of surgery, suggesting failure of intestinal bacterial compartmentalization. In mice, we reveal that hepatic surgery induced dysregulation of i...

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Literature Corpus work: befc4e3b-b90c-50f5-87e8-67b99c91c10b
DOI: 10.1101/773150

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