Article

Acquiring of photosensitivity by Mycobacterium tuberculosis in vitro and inside infected macrophages due to accumulation of endogenous Zn-porphyrins

2023-10-03

Abstract excerpt

Mycobacterium tuberculosis ( Mtb ) is able to transition into a dormant state, causing the latent state of tuberculosis. Dormant mycobacteria acquire resistance to all known antibacterial drugs and can survive in the human body for decades before becoming active. In the dormant forms of M. tuberculosis, the synthesis of porphyrins and Zn-complexes significantly increased when 5-aminolevulinic acid (ALA) was added...

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Literature Corpus work: bee288e5-8025-5a5c-8705-c8a0c88f8f1f
DOI: 10.21203/rs.3.rs-3348857/v1

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